Existen cuatro tipos de grandes familias de tratamientos:
1. Calcioantagonistas
2. Inhibidores de Fosfodiestrasas
3. Prostaciclinas
4. Bloqueadores de Endotelinas
1. Calcioantagonistas
En primer lugar se encuentran los medicamentos llamados calcioantagonistas. Este tipo de medicinas lamentablemente sólo es eficaz para un porcentaje muy pequeño de pacientes con HAP –aproximadamente 10 por ciento.
Para que un médico decida tratarte con un calcioantagonista es necesario que realice pruebas y registre tu reacción hemodinámica ante determinados retos farmacológicos. Esto quiere decir que cuando te hacen un cateterismo cardiaco, el médico usará una sustancia llamada adenosina (podrÃa ser otra) que es un potentÃsimo vasodilatador y, dependiendo, de la reacción que tenga tu presión pulmonar a esa sustancia se te definirá como respondedor o no respondedor.
Las últimas investigaciones médicas han mostrado que para ser considerado como un respondedor es necesario que tu presión pulmonar baje a un nivel considerado como normal. Es decir, a tener una presión pulmonar media de menos de 25 mm de mercurio y una presión sistólica menor a 30 mm de mercurio.
Si eres de los afortunados que resultan respondedores a los calcioantagonistas, tu tratamiento es muchÃsimo más simple y menos costos. Además, las estadÃsticas muestran que los “verdaderos” respondedores a los calcioantagonistas tienen una mucho mejor prognosis.
Es muy importante que el médico que te trata realice las pruebas adecuadas y te ubique de manera rigurosa en el grupo de respondedores o no respondedores. Esto se debe a que el uso de calcioantagonistas con pacientes que no son respondedores puede ser contraproducente y empeorar tu condición.
Otro de los importantes beneficios que tienen los respondedores a calcioantagonistas es que la SecretarÃa de Salud del gobierno de México ha aprobado el uso de calcioantagonistas como tratamiento para la HAP.
Por tanto, el acceso a este tratamiento se simplifica, ya que tanto la seguridad social como los seguros de gastos médicos mayores deben propocionar el medicamento de manera gratuita o cubrir el gasto.
2. Inhibidores de Fosfodiestrasa 5 (PDE-5)
La fosfodiestrasa es una sustancia que se produce en los pulmones y en otras partes del cuerpo que se metaboliza en otra sustancia llamada GMP cÃclica. La GMP cÃclica provoca que los vasos sanguÃneos se relajen y, por tanto, se ensanchen.
Los inhibidores de fosfodiestrasa 5 permiten que haya más GMP cÃclica disponible en los vasos sanguÃneos dentro de los pulmones, permitiendo que éstos se ensanchen y, además, evita la proliferación de células en las paredes de estos vasos sanguÃneos.
Al relajar y ensanchar los vasos sanguÃneos de los pulmones, se hace más fácil el bombeo de sangre del corazón hacia los pulmones. Esto reduce la presión de la sangre en los pulmones, lo que conlleva una mejorÃa en la actividad fÃsica de los pacientes, asà como en su bienestar.
Hasta el momento, el único inhibidor de fosfodiestrasa 5 que está probado como un tratamiento eficaz para la HAP es el viagra cialis online pharmacy pharmacy (Viagra o Revatio)
Sin embargo, se están realizando pruebas clÃnicas de Tadalafil (Cialis).
Sildenafil (Viagra o Revatio)
Es un medicamento oral que se utiliza para el tratamiento de la HAP.
Se realizó un estudio multi-céntrico, llamado SUPER 1, financiado con recursos de la farmacéutica que produce el Sildenafil y este protocolo mostró mejorÃas en la capacidad de ejercicio y menor falta de aliento en los pacientes con HAP.
Los resultados de este estudio están publicados en el ejemplar de noviembre de 2005 del The New England Journal of Medicine. Esta prueba clÃnica fue encabezada por el doctor Nazzarene Galié del Instituto de CardiologÃa de la Universidad de Bologna.
El estudio SUPER 1 se transformó en SUPER 2 con el objetivo de dar seguimiento de más largo plazo a los pacientes –un año. Se mostró una mejora sostenida en la habilidad de ejercicio de más de un año para los pacientes que tomaban sildenafil sólo o en combinación con otro medicamento para la HAP.
Gracias a los resultados el protocolo SUPER 1, la autoridad de salud de Estados Unidos aprobó el uso del Sildenafil para el tratamiento de pacientes con HAP en junio de 2005, comercializado bajo el nombre de Revatio.
El Viagra (tratamiento para la disfunción eréctil) y el Revatio son medicamentos que contienen exactamente la misma sal o sustancia activa (Sildenafil), la única diferencia entre estos dos medicamentos radica en el contenido de sildenafil que cada una de ellas tiene, asà como en su presentación. El viagra se comercializa en pastillas de distintos miligramos y el Revatio en pastillas de 20 miligramos.
La vÃa de administración de este medicamento es bastante simple. Es oral y se administra tres veces al dÃa, en diferentes dosis dependiendo del paciente.
Generalmente la tolerancia de los pacientes al sildenafil es buena. Los efectos secundarios más reportados son: dolor de cabeza, palpitaciones, enrojecimiento, molestias estomacales, mareos, dolores musculares temporales, sangrado de nariz, dificultad para dormir y enrojecimiento.
Lamentablemente las autoridades de salud mexicanas no han aprobado el sildenafil como un tratamiento eficaz para la HAP, a pesar de que en otros paÃses del mundo ya ha sido reconocido.
Taldanafil (Cialis)
Tiene un tiempo de duración mucho mayor, por lo que los pacientes podrÃan sólo tomar una toma al dÃa, en lugar de tres. La prueba clÃnica que se está llevando a cabo se llama PHIRST 1. Inició en agosto de 2005 y actualmente sigue reclutando pacientes. El Taldanafil esta en fase III de aprobación por parte de la FDA.[1]
Supuestamente también tiene menos efectos secundarios
3. Bloqueadores de receptores de endotelina
Las endotelinas son sustancias vasoconstrictoras que se encuentran en las células. Los medicamentos conocidos como bloqueadores de endotelinas son, en realidad, bloqueadores de los receptores de endotelinas que tienen las células. Es decir, lo que bloquea el medicamento es a los receptores para que la sustancia (endotelina) no pueda entrar a la célula.
Existen dos tipos de endotelinas, las endotelinas A (ETA) y las endotelinas B (ETB). Supuestamente las ETA son las que producen la vasoconstricción y las ETB ayudan a la producción de ácido nÃtrico y al desprendimiento de prostaciclina por lo que es una buena sustancia. Esto es una teorÃa.
Todos estos medicamentos son de una toma oral
Dentro de este tipo de medicamentos se encuentran:
A. Bosentan
B. Sitaxentan
C. Ambrisentan
El Bosentan se comercializa con el nombre de Tracleer. Es el medicamento oral pionero para el tratamiento de la HAP. Esta medicina bloquea de manera no selectiva los receptores de endotelina. Es decir, bloquea los receptores de endotelina A y los de endotelina B.
Algunas de sus efectos secundarios más graves es que puede provocar elevación de las enzimas hepáticas.
El Bosentan no es un medicamento aprobado por la SecretarÃa de Salud para el tratamiento de la HAP y no puede conseguirse en México.
Sitaxentan (que ya fue aprobado en Europa, pero todavÃa no en Estados Unidos) y Ambrisentan
El Bosentan es un medicamento que bloquea los receptores de endotelina A y B, mientras que el Sitaxentan y el Ambrisentan bloquea de manera selectiva a los receptores de endotelina A, dejando libre a los receptores de endotelina B.
Los doctores todavÃa se debaten entre la importancia de que el medicamento sea selectivo o no y no han llegado aún a una buena conclusión.
Los bloqueadores de receptores de endotelinas, selectivos o no selectivos, son medicamentos orales que tienen una única dosis diaria. Han probado ser tratamientos que aumentan la capacidad de ejercicio de los pacientes (medido con la prueba de los seis minutos) y también han probado mejorar el funcionamiento hemodinámico de los pacientes.
A pesar de que no existen estudios de largo plazo, se ha mostrado que algunos pacientes se han mantenido estables, atrasando el tiempo de deterioro de los pacientes.
Algunos de los efectos secundarios que se han probado en estos medicamentos son sus efectos tóxicos sobre el hÃgado. Por tanto, la gente que toma este tipo de medicamentos tiene que realizarse pruebas de función hepática cada mes.
4. Prostaciclinas
Las prostaciclinas son el tratamiento de oro para la HAP. La prostaciclina es una sustancia que se produce de manera natural en el cuerpo y su función es dilatar a los vasos sanguÃneos.
El problema de las prostaciclinas es que tienen un ciclo de vida de cortÃsima duración en el ambiente, por lo que la vÃa de administración de este tipo de medicamentos ha sido subcutánea o intravenosa.
Recientemente ha salido al mercado una prostaciclina inhalada y actualmente los laboratorios se encuentran haciendo investigación para lograr tener una prostaciclina cuya vÃa de administración sea oral.
Epoprostenol (Flolan)
Fue aprobado por la FDA como tratamiento de la HAP Primaria en 1995 y posteriormente aprobado para el tratamiento de HAP asociado a escleroderma
El epoprostenol es un análogo de la prostaciclina que ayuda a abrir vasos sanguÃneos de los pulmones constreñidos, reduciendo de esta forma la alta presión en los pulmones.
El epoprostenol tiene una vida de solo unos cuantos minutos, por lo que no puede ser administrado en forma de pÃldora. Se administra continuamente, de manera intravenosa, normalmente mediante un catéter, aunque también puede ser administrado temporalmente de manera intravenosa, mientras los pacientes esperan a que se les coloque el catéter o mientras se cambia el catéter debido a una infección.
Los pacientes usan una bomba de infusión del tamaño de un walkman con un cassette de medicamento, asà como un paquete de hielo.
Una vez que se inicia el tratamiento con epoprostenol, no debe pararse de manera abrupta, ni la dosis debe ser reducida de manera drástica, a menos de que un especialista en PH señale que es necesario.
Una breve interrupción del medicamento puede provocar la muerte.
Muchos pacientes se benefician del Flolan, especialmente aquellos con HP severa.
Los efectos secundarios más comunes son enrojecimiento, dolor de pies, dolor de mandÃbula, diarrea y dolores musculares en las pantorrillas y en los pies, nausea, vomito y dolores de cabeza. También pueden ocurrir problemas de tiroides y bocio.
Una sobredosis de Flolan puede ocasionar una drástica caÃda de la presión sanguÃnea.
En México muy poca gente utiliza Flolan.
Teprostinil (Remodulin o UT-15)
La marca del treprostinil se conoce como Remodulin. Es una prosctaciclina análoga que se usa para abrir los vasos sanguÃneos constreñidos. Se administra por medio de una infusión subcutánea o intravenosa continua.
Cuando se administra de manera subcutánea, el treprostinil se bombea a la grasa debajo de la piel, y los pacientes se conectan en el estómago, la cadera, las pompas o el brazo cada X dÃas con una aguja que tiene media pulgada de largo y está conectada por un catéter largo de plástico a la bomba. La aguja se retira, pero el catéter permanece. Una gota a gota, la medicina se mete debajo de la piel. 85 por ciento de los usuarios han reportado dolor cuando la medicina entra en el cuerpo y la sensación de dolor varÃa dramáticamente de paciente a paciente, incluso de lugar a lugar del cuerpo en el que se coloca el catéter.
Otros efectos secundarios incluyen dolor de mandÃbula en la primera mordida, diarrhea moderada, enrojecimiento, dolor de cabeza, nausea, enrojecimiento, mareo, edema, comezón e hipotensión.
Iloprost (Ventavis)
Iloprost se vende con el nombre de Ventavis. Es otra prostaciclina análoga que puede tomarse de manera inhalada o inyectada. Su uso para HAP en Estados Unidos está aprobado de forma inhalada.
Cuando el iloprost se inhala, se cree que sus efectos se confinan mayoritariamente a los pulmones, por lo que reduce la mayorÃa de los efectos secundarios. Los usuarios de iloprost inhalan entre 6 y 9 veces durante el dÃa y no inhalan por las noches.
Un problema del iloprost inhalado es que sus beneficios desaparecen en 30 a 90 minutos, por lo que los pacientes tienen que inhalar muchas veces al dÃa.
Los efectos secudnarios que han reportado los pacientes son tos, enrojecimiento, dolor de cabeza, y dolor de mandÃbula.
Teprostinil oral (en investigación)
Existen dos protocolos (FREEDOM) de investigación que se están llevando a cabo. Uno para probar el teprostinil oral como monoterapia, empezó en mayo de 2006, y el otro como terapia combinada, mayo de 2006.
Fuente de informacion, colaboradora de FAHIP, Congreso de Mineapolis.
Tuesday, November 1, 2011
Saturday, October 29, 2011
What You must Know about Desyrel
See also: online pharmacy viagra |
About the Author:
Desyrel is part of the category of prescription drugs also known as atypical antipsychotic medicines. Even though it's not necessarily best-known precisely how it works, it is usually recognized it works to prevent the effects of quite a few chemical compounds, including serotonin and dopamine, which are usually found inside the brain. These chemical substances tend to be almost always raised with individuals which are schizophrenic or maybe experience together with bi-polar condition. While not relief from the two of these problems, it will eventually work to restrain this symptoms.
Psychosis is referred to as an abnormal condition of the mind and as a severing or detachment of reality. It is not uncommon for sufferers of the condition to vary in their signs but most of them usually experience vivid hallucinations and delusional thoughts. Depending on the stage of the disease, patients might experience hearing voices which are either commanding or quiet.
Both psychological and medical problems can cause this condition. But the most recognized and common include electrolyte problems, depression, lack of sleep, Lyme disease, and brain malignancies. The condition may also be triggered by external factors which include medications and mumps inoculations.
Just like several medicinal drugs with this class, this would cause dangerous side effects. Most side effects are short term and most people definitely will adjust to the current treatment properly. A number of uncomfortable side effects really are minor and include drowsiness, dizziness, wiggling, headaches and bodyweight gain. Other common side effects contain symptoms of heartburn, bowel problems and dry mouth.
This was initially given a black box label by the FDA , thanks to its increased death rate among older individuals. This medication also increases the risk of fatal cardiovascular problems in some patients. And for those with bipolar disorders, this can cause mania. Doctors should monitor carefully their patients and observe if any of these side effects will occur.
The pill's other side effects include insomnia, dizzy spells, fatigue, temporary speech disorders, and severe chest pain. Even though it hasn't yet been proven, testing conducted recently by the FDA suggests that anti psychotic medicines can put some patients at a higher risk of hyperglycemia and diabetes. Animal testing has shown significant increases in the amounts of birth defects but this has not yet been confirmed in humans.
The manufacturer of the drug was ordered by the FDA to pay a giant fine in 2009 for misbranding the purpose and success rate of their product. Since then, several studies suggest that the pill is a much safer alternative to other anti psychosis drugs.
Psychosis is referred to as an abnormal condition of the mind and as a severing or detachment of reality. It is not uncommon for sufferers of the condition to vary in their signs but most of them usually experience vivid hallucinations and delusional thoughts. Depending on the stage of the disease, patients might experience hearing voices which are either commanding or quiet.
Both psychological and medical problems can cause this condition. But the most recognized and common include electrolyte problems, depression, lack of sleep, Lyme disease, and brain malignancies. The condition may also be triggered by external factors which include medications and mumps inoculations.
Just like several medicinal drugs with this class, this would cause dangerous side effects. Most side effects are short term and most people definitely will adjust to the current treatment properly. A number of uncomfortable side effects really are minor and include drowsiness, dizziness, wiggling, headaches and bodyweight gain. Other common side effects contain symptoms of heartburn, bowel problems and dry mouth.
This was initially given a black box label by the FDA , thanks to its increased death rate among older individuals. This medication also increases the risk of fatal cardiovascular problems in some patients. And for those with bipolar disorders, this can cause mania. Doctors should monitor carefully their patients and observe if any of these side effects will occur.
The pill's other side effects include insomnia, dizzy spells, fatigue, temporary speech disorders, and severe chest pain. Even though it hasn't yet been proven, testing conducted recently by the FDA suggests that anti psychotic medicines can put some patients at a higher risk of hyperglycemia and diabetes. Animal testing has shown significant increases in the amounts of birth defects but this has not yet been confirmed in humans.
The manufacturer of the drug was ordered by the FDA to pay a giant fine in 2009 for misbranding the purpose and success rate of their product. Since then, several studies suggest that the pill is a much safer alternative to other anti psychosis drugs.
About the Author:
Ruho Yahyani is recognized as a specialist in every aspects related about health. The author is definitely focused on intensive study of medications similar to Desyrel to generate every item's effectivity. Uncover the benefits related to Desyrel.
Monday, May 23, 2011
Watermelon is nature's Viagra
Watermelon is nature's Viagra
If you thought watermelon is just a fruit that refreshes parched throats, here’s something you should know - the juicy fruit has ingredients that deliver Viagra-like effects to the body’s blood vessels and may even increase libido.
The finding results from a study led by an Indian researcher in US. “The more we study watermelons, the more we realize just how amazing a fruit it is in providing natural enhancers to the human body,” said Dr. Bhimu Patil, director of Texas A&M’s Fruit and Vegetable Improvement Center. "We’ve always known that watermelon is good for you, but the list of its very important health benefits grows longer with each study,” he added.
Beneficial ingredients in watermelon and other fruits and vegetables are known as phyto-nutrients, naturally occurring compounds that are bioactive, or able to react with the human body to trigger healthy reactions, Patil said. In watermelons, these include lycopene, beta carotene and the rising star among its phyto-nutrients – citrulline, whose beneficial functions are now being unraveled. It has the ability to relax blood vessels, much like cheap viagra does.
Scientists know that when watermelon is consumed, citrulline is converted to arginine through certain enzymes. Arginine is an amino acid that works wonders on the heart and circulation system and maintains a good immune system, Patil said. “The citrulline-arginine relationship helps heart health, the immune system and may prove to be very helpful for those who suffer from obesity and type 2 diabetes,” said Patil. “Arginine boosts nitric oxide, which relaxes blood vessels, the same basic effect that cialis has, to treat erectile dysfunction and maybe even prevent it,” he added.
While there are many psychological and physiological problems that can cause impotence, extra nitric oxide could help those who need increased blood flow, which would also help treat angina, high blood pressure and other cardiovascular problems.
“Watermelon may not be as organ specific as Viagra, but it’s a great way to relax blood vessels without any drug side-effects,” Patil said.
The benefits of watermelon don’t end there, he said. Arginine also helps the urea cycle by removing ammonia and other toxic compounds from our bodies. Citrulline, the precursor to arginine, is found in higher concentrations in the rind of watermelons than the flesh.
- Times of India.
Pubmed indexed 637 research articles on watermelon. Below are latest 20 articles.
1: Tarachiwin L, Masako O, Fukusaki E.
Quality Evaluation and Prediction of Citrullus lanatus by (1)H NMR-Based
Metabolomics and Multivariate Analysis.
J Agric Food Chem. 2008 Jun 28. [Epub ahead of print]
PMID: 18588311
2: van Breemen RB, Pajkovic N.
Multitargeted therapy of cancer by lycopene.
Cancer Lett. 2008 Jun 26. [Epub ahead of print]
PMID: 18585855
3: Bangalore DV, McGlynn WG, Scott DD.
Effects of fruit maturity on watermelon ultrastructure and intracellular lycopene
distribution.
J Food Sci. 2008 Jun;73(5):S222-8.
PMID: 18577014
4: Gholamalizadeh R, Vahdat A, Keshavarz T, Elahinia A, Bananej K.
Occurrence and distribution of ten viruses infecting cucurbit plants in guilan
province, iran.
Acta Virol. 2008;52(2):113-8.
PMID: 18564898
5: Wechter WP, Levi A, Harris KR, Davis AR, Fei Z, Katzir N, Giovannoni JJ,
Salman-Minkov A, Hernandez A, Thimmapuram J, Tadmor Y, Portnoy V, Trebitsh T.
Gene expression in developing watermelon fruit.
BMC Genomics. 2008 Jun 5;9:275.
PMID: 18534026
6: Wells CD, Harrison ME, Gurudu SR, Crowell MD, Byrne TJ, Depetris G, Sharma VK.
Treatment of gastic antral vascular ectasia (watermelon stomach) with endoscopic
band ligation.
Gastrointest Endosc. 2008 Jun 2. [Epub ahead of print]
PMID: 18533150
7: Farooq Z, Iqbal Z, Mushtaq S, Muhammad G, Iqbal MZ, Arshad M.
Ethnoveterinary practices for the treatment of parasitic diseases in livestock in
Cholistan desert (Pakistan).
J Ethnopharmacol. 2008 Jul 23;118(2):213-9. Epub 2008 Mar 29.
PMID: 18524514
8: Kumar S, Kumar D, Jusha M, Saroha K, Singh N, Vashishta B.
Antioxidant and free radical scavenging potential of Citrullus colocynthis (L.)
Schrad. methanolic fruit extract.
Acta Pharm. 2008 Jun 1;58(2):215-221.
PMID: 18515231
9: Marie I, Ducrotte P, Antonietti M, Herve S, Levesque H.
Watermelon stomach in systemic sclerosis: its incidence and management.
Aliment Pharmacol Ther. 2008 May 21. [Epub ahead of print]
PMID: 18498445
10: Asero R, Monsalve R, Barber D.
Profilin sensitization detected in the office by skin prick test: a study of
prevalence and clinical relevance of profilin as a plant food allergen.
Clin Exp Allergy. 2008 Jun;38(6):1033-7. Epub 2008 Apr 13.
PMID: 18489029
11: Yakoubi S, Lecoq H, Desbiez C.
Algerian watermelon mosaic virus (AWMV): a new potyvirus species in the PRSV
cluster.
Virus Genes. 2008 Aug;37(1):103-9. Epub 2008 May 17.
PMID: 18484176
12: Hoelmer KA, Simmons AM.
Yellow sticky trap catches of parasitoids of Bemisia tabaci (Hemiptera:
Aleyrodidae) in vegetable crops and their relationship to in-field populations.
Environ Entomol. 2008 Apr;37(2):391-9.
PMID: 18419911
13: Vonderheide AP, Bernard CE, Hieber TE, Kauffman PE, Morgan JN, Melnyk LJ.
Surface-to-food pesticide transfer as a function of moisture and fat content.
J Expo Sci Environ Epidemiol. 2008 Apr 16. [Epub ahead of print]
PMID: 18414514
14: Mullai K, Jebanesan A, Pushpanathan T.
Mosquitocidal and repellent activity of the leaf extract of Citrullus vulgaris
(cucurbitaceae) against the malarial vector, Anopheles stephensi liston (diptera
culicidae).
Eur Rev Med Pharmacol Sci. 2008 Jan-Feb;12(1):1-7.
PMID: 18401966 [PubMed - indexed for MEDLINE]
15: Mort A, Zheng Y, Qiu F, Nimtz M, Bell-Eunice G.
Structure of xylogalacturonan fragments from watermelon cell-wall pectin.
Endopolygalacturonase can accommodate a xylosyl residue on the galacturonic acid
just following the hydrolysis site.
Carbohydr Res. 2008 May 19;343(7):1212-21. Epub 2008 Mar 20.
PMID: 18394594
16: Pieroni A, Gray C.
Herbal and food folk medicines of the Russlanddeutschen living in
Künzelsau/Taläcker, South-Western Germany.
Phytother Res. 2008 Jul;22(7):889-901.
PMID: 18384192
17: Vaughn Katherine LS, Clausen Edgar C, King Jerry W, Howard Luke R, Julie CD.
Extraction conditions affecting supercritical fluid extraction (SFE) of lycopene
from watermelon.
Bioresour Technol. 2008 Nov;99(16):7835-41. Epub 2008 Apr 2.
PMID: 18378137
18: Bailey SL, Chang SC, Griffiths B, Graham AN, Saffery R, Earle E, Choo KH,
Kalitsis P.
ZNF397, a new class of interphase to early prophase-specific, SCAN-zinc-finger,
mammalian centromere protein.
Chromosoma. 2008 Mar 28. [Epub ahead of print]
PMID: 18369653
19: Sreenath K, Venkatesh YP.
Analysis of erythritol in foods by polyclonal antibody-based indirect competitive
ELISA.
Anal Bioanal Chem. 2008 Mar 28. [Epub ahead of print]
PMID: 18369603
20: Salman-Minkov A, Levi A, Wolf S, Trebitsh T.
ACC synthase genes are polymorphic in watermelon (Citrullus spp.) and
differentially expressed in flowers and in response to auxin and gibberellin.
Plant Cell Physiol. 2008 May;49(5):740-50. Epub 2008 Mar 26.
PMID: 18367517
Tuesday, May 3, 2011
Weigh In Day is Here!
See also: cialis |
So this week was a bit different... and yesterday, I figured was a wash, a disaster of a day... maybe not?
I wanted to get my workout in first thing in the morning yesterday due to a packed day of things to get done and hubby is off on a biz trip again this week.
So this week was a bit different... and yesterday, I figured was a wash, a disaster of a day... maybe not?
I wanted to get my workout in first thing in the morning yesterday due to a packed day of things to get done and hubby is off on a biz trip again this week.
So I headed down to the basement to get my workout in... heard the door and the dogs so I came up... it was the Mailman dropping off the parts for our BBQ, which had fallen over during the Spring in a windstorm. The main handle supports had broken off. Yaaay! we can BBQ again... that is when SPRING GETS HERE! lol!! Had snow twice this week.
After opening the package, I was going to head back down to add to my workout, then my son tells me that his worker is coming 15 min later... which would be any time soon, so I figured, might as well wait to go back to working out.
So I grabbed a Protein Shake, then after the meeting, headed back down to finish what I started... not to be.
I am 20 min into my workout, my son, who is normally NOT home when I am working out, walks into the gym with the phone... I'm like, who's on the phone, he says no body but, it keeps ringing. I am a bit ticked at this point.
I explained to him... the only time you come down here is to tell me the house is on fire, the police are at the door, or there is some sort of emergency that needs my attention immediately. If the JW come to the door, tell them to come back another time, if there is a friend at the door, tell them to come in, offer them a drink, tell them I will be with them shortly. BUT NEVER come downstairs with a phone in your hand cause it rings!! If its important, they will leave a message and I can see who called and will call them back!
WORKOUT ATTEMPT #2 SHOT!
At this point, I have to head out shortly so... might as well call it a wash at this point until later tonight.
Made a Seaweed Salad with Shrimp and called it lunch!
Dinner was Pasta, Red Sauce and Chicken TVP Meatballs and a salad, serving sizes of course! And an hour later...
I gave instructions to both kids... Fire, Police, Ambulance, Emergency ONLY, otherwise DO NOT DISTURB!!! lol!!
So in total, yesterday was a 75 min workout.
So what did I find that works best? Well this is for me! Cause if you have medical conditions, this might not be good for you, check with your purchase cialis.
I found that working out on an empty stomach, which is what they do on the biggest loser, WORKS very well for me. I don't wake up, ravaging hungry in the mornings... I have my Latte, and certain supplements that HAVE to be taken on an empty stomach, then within 2 hours, I workout for 1 hour. I also found that wearing those "sweat shorts" work as well. Man do you sweat! lol!!
A WARNING: This type of training is hard on the body. LITERALLY!! Once you have used up all the glycogen (muscle food) that is stored in the muscle, your body WILL use the fat reserves because you haven't put any food into your body. This IS PAINFUL on the muscles, in particular, the long muscles, such as Quads (front upper leg) and Hamstrings (back upper legs). And I STRONGLY advise you speak to your medical practitioner before attempting this kind of training.
I have also increased my calories, ever so slightly, equal to about one snack a day... and it seems to be working...
Working to the tune of 3 more pounds gone and a grand total of 16lbs in just over 1 month!
When I get a few more pounds down, I will started adding the before and during pictures.
One thing I constantly remind myself of...
I didn't gain all this weight in one day, it was over a period of years and menopause hitting me lol!! Pros and Cons on that one!! lol!! So... I have to keep my expectations in check that it will take the same amount of time, maybe a little less, to take it all off.
Stay focused and keep moving!!! :o)
Headache Medicine
Saturday, September 5, 2009
When people get a headache they usually start searching for some medication that can stop their headache from becoming much worse. As there are so many different kinds of headache medication to choose from, people have to think about what they want the treatment to accomplish.
The headache medicines that are found at the supermarkets and pharmacies come in various forms. You will find that there are cheap cialis you can take, cheap cialis that dissolve under your tongue, nasal sprays, suppositories, and injections that you administer yourself. All of these headache medication are known to work well at preventing your headache from developing into something much worse.
When you go for headache medicine on a supermarket shelf, you need to decide how fast-acting you want the treatment to be. We are normally used to taking pills and capsules to cure whatever ailments that we have. We take these types of medications because they are easy to take and easy to take with us.
While these types of headache medicine do work for most people, it takes a little time for the treatment to take effect. For this reason any person who has a severe type of headache like a migraine, will not benefit from these tablets or capsules. Also the various fast-developing headaches will not do well either with these medicines.
People who have a tension type headache, a slow-acting migraine attack or a migraine attack without nausea and vomiting, can use these tablets. There are tablets that you can use that are absorbed more quickly into your bloodstream. These so-called 'sub-lingual' tablets or lozenges are put under the tongue, where they are absorbed by the membrane that lines the mouth. These kinds of headache medication work a little more quickly than the normal tablets as they are absorbed directly and so more quickly into the bloodstream.
The other way that you can stop your headache is with a nasal spray. These sprays provide you with fast-acting relief. They are good for headache sufferers who need fast relief and they are also good for people who have the symptoms of nausea and vomiting. You may have to test various brands before you get satisfactory results, but these headache medicines are still quite good.
The best possible pain relief can be got quickly from self injected drugs. However, if you take this type headache medicine you will have to take extra care at first, to ensure that you don't inject yourself with too much of the headache drug.
Another consideration is whether you can put up with the discomfort that you may first feel when you try to inject yourself. The possible embarrassment about injecting yourself in public with your headache treatment is also something that you will have to think about.
There is a vast amount of headache medicine for the person who is looking for ways to cure their headache misery. The best way to find your right medication is to test different products in order to see what works best for you.
The headache medicines that are found at the supermarkets and pharmacies come in various forms. You will find that there are cheap cialis you can take, cheap cialis that dissolve under your tongue, nasal sprays, suppositories, and injections that you administer yourself. All of these headache medication are known to work well at preventing your headache from developing into something much worse.
When you go for headache medicine on a supermarket shelf, you need to decide how fast-acting you want the treatment to be. We are normally used to taking pills and capsules to cure whatever ailments that we have. We take these types of medications because they are easy to take and easy to take with us.
While these types of headache medicine do work for most people, it takes a little time for the treatment to take effect. For this reason any person who has a severe type of headache like a migraine, will not benefit from these tablets or capsules. Also the various fast-developing headaches will not do well either with these medicines.
People who have a tension type headache, a slow-acting migraine attack or a migraine attack without nausea and vomiting, can use these tablets. There are tablets that you can use that are absorbed more quickly into your bloodstream. These so-called 'sub-lingual' tablets or lozenges are put under the tongue, where they are absorbed by the membrane that lines the mouth. These kinds of headache medication work a little more quickly than the normal tablets as they are absorbed directly and so more quickly into the bloodstream.
The other way that you can stop your headache is with a nasal spray. These sprays provide you with fast-acting relief. They are good for headache sufferers who need fast relief and they are also good for people who have the symptoms of nausea and vomiting. You may have to test various brands before you get satisfactory results, but these headache medicines are still quite good.
The best possible pain relief can be got quickly from self injected drugs. However, if you take this type headache medicine you will have to take extra care at first, to ensure that you don't inject yourself with too much of the headache drug.
Another consideration is whether you can put up with the discomfort that you may first feel when you try to inject yourself. The possible embarrassment about injecting yourself in public with your headache treatment is also something that you will have to think about.
There is a vast amount of headache medicine for the person who is looking for ways to cure their headache misery. The best way to find your right medication is to test different products in order to see what works best for you.
About the Author:
If you have a problem with migraine headaches, you ought to definitely go to our website at http://stopping-headaches.the-real-way.com. Visit the Uber Article Directory to get a totally unique version of this article for reprint.
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